RNF150 suppresses thyroid carcinoma by inactivating the p38 pathway via ubiquitination of ASK1.
Sign Up to like & getrecommendations! Published in 2022 at "Cell biology international"
DOI: 10.1002/cbin.11786
Abstract: Thyroid carcinoma (THCA) is the most prevalent cancer in endocrine system. However, the pathogenic mechanism underlying tumor recurrence remains unclear. RING finger protein (RNF) family plays a crucial role in cancers whereas the role of… read more here.
Keywords: inactivating p38; thyroid carcinoma; rnf150; rnf150 thca ... See more keywords
Carnosic acid (CA) attenuates collagen‐induced arthritis in db/db mice via inflammation suppression by regulating ROS‐dependent p38 pathway
Sign Up to like & getrecommendations! Published in 2017 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2017.03.023
Abstract: Abstract Rheumatoid arthritis (RA) is a multifactorial autoimmune disease, characterized by inflammation of synovial joints. Carnosic acid (CA) is a phenolic diterpene isolated from Rosmarinus officinailis, playing a central role in cytoprotective responses to oxidative… read more here.
Keywords: dependent p38; inflammation; ros dependent; acid ... See more keywords
Interleukin‐38 suppresses abdominal aortic aneurysm formation in mice by regulating macrophages in an IL1RL2‐p38 pathway‐dependent manner
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DOI: 10.14814/phy2.15581
Abstract: Macrophages play crucial roles in abdominal aortic aneurysm (AAA) formation through the inflammatory response and extracellular matrix degradation; therefore, regulating macrophages may suppress AAA formation. Interleukin‐38 (IL‐38) is a member of the IL‐1 family, which… read more here.
Keywords: aaa formation; aortic aneurysm; abdominal aortic; regulating macrophages ... See more keywords
The p38 pathway, a major pleiotropic cascade that transduces stress and metastatic signals in endothelial cells
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DOI: 10.18632/oncotarget.18264
Abstract: By gating the traffic of molecules and cells across the vessel wall, endothelial cells play a central role in regulating cardiovascular functions and systemic homeostasis and in modulating pathophysiological processes such as inflammation and immunity.… read more here.
Keywords: p38; endothelial cells; stress metastatic; p38 p38 ... See more keywords