Rongjin Niantong Fang ameliorates cartilage degeneration by regulating the SDF-1/CXCR4-p38MAPK signalling pathway
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DOI: 10.1080/13880209.2022.2143533
Abstract: Abstract Context Rongjin Niantong Fang (RJNTF) is a Traditional Chinese Medicine formulation with a good therapeutic effect on osteoarthritis (OA). However, the underlying mechanisms remain unclear. Objective This study investigates whether RJNTF could delay OA… read more here.
Keywords: cxcr4 p38mapk; p38mapk signalling; sdf cxcr4; group ... See more keywords
Inhibition of p38MAPK signalling prevents epidermal blistering and alterations of desmosome structure induced by pemphigus autoantibodies in human epidermis
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DOI: 10.1111/bjd.15721
Abstract: Pemphigus vulgaris (PV) is a skin blistering disease caused by autoantibodies targeting the desmosomal adhesion proteins desmoglein (Dsg) 3 and 1. The mechanisms underlying pemphigus skin blistering are not fully elucidated but p38 mitogenâactivated protein… read more here.
Keywords: p38mapk signalling; epidermal blistering; signalling prevents; inhibition p38mapk ... See more keywords