GSH/GSSG redox couple plays central role in aryl hydrocarbon receptor‐dependent modulation of cytochrome P450 1A1
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22164
Abstract: The redox regulation of aryl hydrocarbon receptor (AHR) target genes such as the best characterized, cytochrome P450 1A1 (CYP1A1) has not been known. Therefore the aim of this study was to explore how cellular redox… read more here.
Keywords: gssg; p450 1a1; hydrocarbon receptor; aryl hydrocarbon ... See more keywords
Sensing cytochrome P450 1A1 activity by a resorufin-based isoform-specific fluorescent probe
Sign Up to like & getrecommendations! Published in 2020 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2020.05.038
Abstract: Abstract Cytochrome P450 1A1 (CYP1A1), a heme-containing monooxygenase, is of particular importance for human health because of its vital roles in the metabolic activation of pro-carcinogenic compounds to the carcinogens. Deciphering the relevance of CYP1A1… read more here.
Keywords: p450 1a1; cyp1a1; isoform specific; cytochrome p450 ... See more keywords
Cytochrome P450 1A1 (CYP1A1) Catalyzes Lipid Peroxidation of Oleic Acid-Induced HepG2 Cells
Sign Up to like & getrecommendations! Published in 2018 at "Biochemistry (Moscow)"
DOI: 10.1134/s0006297918050127
Abstract: Nonalcoholic fatty liver disease (NAFLD) is a chronic hepatic disease associated with excessive accumulation of lipids in hepatocytes. As the disease progresses, oxidative stress plays a pivotal role in the development of hepatic lipid peroxidation.… read more here.
Keywords: p450 1a1; cyp1a1; lipid peroxidation; peroxidation ... See more keywords