Electrochemical detection of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone using a cytochrome P450 2E1 decorated biosensor
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Electroanalytical Chemistry"
DOI: 10.1016/j.jelechem.2018.03.038
Abstract: Abstract In this work, a novel electrochemical biosensor for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) was developed based on cytochrome P450 2E1 (CYP2E1). The biosensor was fabricated by immobilization of CYP2E1 with poly (diallyldimethylammonium chloride) (PDDA) - poly (sodium-p-styrenesulfonate)… read more here.
Keywords: detection; biosensor; p450 2e1; pyridyl butanone ... See more keywords
Cytochrome P450-2E1 promotes fast food-mediated hepatic fibrosis
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DOI: 10.1038/srep39764
Abstract: Cytochrome P450-2E1 (CYP2E1) increases oxidative stress. High hepatic cholesterol causes non-alcoholic steatohepatitis (NASH) and fibrosis. Thus, we aimed to study the role of CYP2E1 in promoting liver fibrosis by high cholesterol-containing fast-food (FF). Male wild-type… read more here.
Keywords: fast food; fibrosis; food mediated; p450 2e1 ... See more keywords