Articles with "p450 glo" as a keyword



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Identification of Selective CYP3A7 and CYP3A4 Substrates and Inhibitors Using a High-Throughput Screening Platform

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Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.899536

Abstract: Cytochrome P450 (CYP) 3A7 is one of the major xenobiotic metabolizing enzymes in human embryonic, fetal, and newborn liver. CYP3A7 expression has also been observed in a subset of the adult population, including pregnant women,… read more here.

Keywords: cyp3a7; identification selective; p450 glo; metabolic stability ... See more keywords