Cytochrome P450 Mining for Bufadienolide Diversification.
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DOI: 10.1021/acschembio.4c00089
Abstract: Bufadienolides are a class of steroids with a distinctive α-pyrone ring at C17, mostly produced by toads and consisting of over 100 orthologues. They exhibit potent cardiotonic and antitumor activities and are active ingredients of… read more here.
Keywords: p450; mining bufadienolide; p450 mining; bufalin ... See more keywords