New insecticide screening platforms indicate that Mitochondrial Complex I inhibitors are susceptible to cross-resistance by mosquito P450s that metabolise pyrethroids
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DOI: 10.1038/s41598-020-73267-x
Abstract: Fenazaquin, pyridaben, tolfenpyrad and fenpyroximate are Complex I inhibitors offering a new mode of action for insecticidal malaria vector control. However, extended exposure to pyrethroid based products such as long-lasting insecticidal nets (LLINs) has created… read more here.
Keywords: complex inhibitors; cross resistance; p450s metabolise; resistance ... See more keywords