NFκB2 p52 stabilizes rhogdiβ mRNA by inhibiting AUF1 protein degradation via a miR‐145/Sp1/USP8‐dependent axis
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.22970
Abstract: Although overexpression of the non‐canonical NFκB subunit p52 has been observed in several tumors, the function and mechanism of p52 in bladder cancer (BC) are less well understood. Here, we aimed at understanding the role… read more here.
Keywords: invasion; rhogdi mrna; protein degradation; auf1 protein ... See more keywords
NF-κB/p52 augments ETS1 binding genome-wide to promote glioma progression
Sign Up to like & getrecommendations! Published in 2023 at "Communications Biology"
DOI: 10.1101/2023.01.11.523507
Abstract: p52-induced ETS1 overexpression in glioma cells remodels the genome-wide regulatory network of p52 and ETS1 to transcriptionally drive cancer progression. Gliomas are highly invasive and chemoresistant cancers, making them challenging to treat. Chronic inflammation is… read more here.
Keywords: p52; p52 ets1; genome wide; glioma progression ... See more keywords
Expression of p52, a non-canonical NF-kappaB transcription factor, is associated with poor ovarian cancer prognosis
Sign Up to like & getrecommendations! Published in 2020 at "Biomarker Research"
DOI: 10.1186/s40364-020-00227-y
Abstract: Background The canonical and non-canonical nuclear factor-kappaB (NF-κB) signaling pathways have key roles in cancer, but studies have previously evaluated only the association of canonical transcription factors and ovarian cancer survival. Although a number of… read more here.
Keywords: progression; non canonical; ovarian cancer; cancer ... See more keywords