The Novel mTOR Complex 1/2 Inhibitor P529 Inhibits Human Lung Myofibroblast Differentiation
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DOI: 10.1002/jcb.25878
Abstract: Idiopathic pulmonary fibrosis is a progressive and deadly disorder with very few therapeutic options. Palomid 529 (8‐(1‐hydroxyethyl)‐2‐methoxy‐3‐(4‐methoxybenzyloxy)‐benzo[c]chromen‐6‐one; P529) is a novel dual inhibitor of mechanistic target of rapamycin complex 1/2 (mTORC1/2). In these studies, we… read more here.
Keywords: myofibroblast differentiation; human lung; tgf induced; p529 ... See more keywords