Small p53 derived peptide suitable for robust nanobodies dimerization.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of immunological methods"
DOI: 10.1016/j.jim.2021.113144
Abstract: Bivalent VHHs have been shown to display better functional affinity compared with their monovalent counterparts. Bivalency can be achieved either by inserting a hinge region between both VHHs units or by using modules that lead… read more here.
Keywords: dimerization; p53 derived; small p53; peptide suitable ... See more keywords
P53-derived hybrid peptides induce apoptosis of synovial fibroblasts in the rheumatoid joint
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.23268
Abstract: Loss of p53-mediated suppression by its dominant-negative counterpart is commonly observed in human cancers, and activating p73 is a therapeutic strategy in p53-mutated oncological patients. In synovial fibroblasts (SFs) from rheumatoid arthritis (RA), mutant p53… read more here.
Keywords: derived hybrid; p53 derived; hybrid peptides; induce apoptosis ... See more keywords