Effect of KRAS mutations and p53 expression on the postoperative prognosis of patients with colorectal cancer
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.1905
Abstract: In the occurrence and development of colorectal cancer, p53 is an important regulator downstream of the MAPK signaling pathway and plays an important role in inhibiting abnormal proliferation signals generated by KRAS mutations. The purpose… read more here.
Keywords: kras mutations; p53 expression; colorectal cancer; mutations p53 ... See more keywords
p53 expression and subcellular survivin localization improve the diagnosis and prognosis of patients with diffuse astrocytic tumors
Sign Up to like & getrecommendations! Published in 2017 at "Cellular Oncology"
DOI: 10.1007/s13402-017-0361-5
Abstract: PurposeDiffuse astrocytic tumors are the most frequently occurring primary central nervous system (CNS) tumors. Their histological sub-classification into diffuse astrocytoma (DA), anaplastic astrocytoma (AA) and glioblastoma (GB) is challenging and the available prognostic factors are… read more here.
Keywords: diffuse astrocytic; survivin; expression; p53 expression ... See more keywords
Ki-67 and p53 expression in head and neck mucosal melanoma: A clinicopathologic analysis of predictors of outcome.
Sign Up to like & getrecommendations! Published in 2021 at "Annals of diagnostic pathology"
DOI: 10.1016/j.anndiagpath.2021.151789
Abstract: OBJECTIVE To explore the prognostic value of Ki-67 and p53 in patients with head and neck mucosal melanoma by analyzing the relevant data from previous patients. METHODS Data on Ki-67 and p53 immunohistochemical staining in… read more here.
Keywords: mucosal melanoma; neck mucosal; expression; p53 expression ... See more keywords
TERTp mutations and p53 expression in head and neck cutaneous basal cell carcinomas with different aggressive features
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-89906-w
Abstract: Cutaneous basal cell carcinoma (cBCC) is an economic burden to health services, due to its great morbidity and increasing incidence in old people. Infiltrative cBCCs and cBCCs with micronodular pattern are considered as more aggressive.… read more here.
Keywords: cbccs; tertp mutation; expression; p53 expression ... See more keywords
Comparative study of Her-2, p53, Ki-67 expression and clinicopathological characteristics of breast cancer in a cohort of northern China female patients
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DOI: 10.1080/21655979.2016.1235101
Abstract: ABSTRACT The objective was to study the relationship among Her-2, Ki-67, p53 expression and the clinicopathologic characteristics of breast cancer in the patients of northern China. Expression of Her-2, Ki-67, p53 and clinical characteristics of… read more here.
Keywords: p53 expression; expression; breast cancer;
The Telomerase Activity of Selenium-Induced Human Umbilical Cord Mesenchymal Stem Cells Is Associated with Different Levels of c-Myc and p53 Expression.
Sign Up to like & getrecommendations! Published in 2017 at "DNA and cell biology"
DOI: 10.1089/dna.2016.3411
Abstract: Selenium-as a trace element-is nutritionally essential for humans. It prevents cancerous growth by inhibiting the telomerase activity but the mechanism involved in regulation of telomerase activity in normal telomerase-positive cells remains to be elucidated. Here,… read more here.
Keywords: myc p53; telomerase activity; p53 expression; telomerase ... See more keywords
Negative p53 Expression Confers Worse Prognosis in Patients With Resected Pancreatic Ductal Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Pancreas"
DOI: 10.1097/mpa.0000000000002175
Abstract: Abstract Objective The aim of the study is to reinterpret the prognostic prediction of p53 expression categories in pancreatic ductal adenocarcinoma with exploration of the relationship between TP53 mutation genotype and p53 expression pattern. Methods… read more here.
Keywords: pancreatic ductal; p53 expression; ductal adenocarcinoma; expression ... See more keywords
Altered Rb, p16, and p53 expression is specific for porocarcinoma relative to poroma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cutaneous Pathology"
DOI: 10.1111/cup.13480
Abstract: Porocarcinomas are rare aggressive carcinomas that harbor tumor suppressor mutations and must be distinguished from benign entities such as poromas. read more here.
Keywords: altered p16; p16 p53; specific porocarcinoma; porocarcinoma relative ... See more keywords
Loss of p53 Expression in Gastric Epithelial Cells of Helicobacter pylori-Infected Jordanian Patients
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Microbiology"
DOI: 10.1155/2022/7779770
Abstract: Background Around half of the global population is chronically infected with the stomach bacterium Helicobacter pylori, making it one of the most common chronic infections worldwide. H. pylori induces the production of reactive oxygen species,… read more here.
Keywords: expression; p53 expression; pylori infection; helicobacter pylori ... See more keywords
Aberrant p53 Expression in Gastric Biopsies and Resection Specimens Following Neoadjuvant Chemoradiation: A Diagnostic Pitfall.
Sign Up to like & getrecommendations! Published in 2023 at "International journal of surgical pathology"
DOI: 10.1177/10668969231157304
Abstract: Gastric mucosal biopsies and resections from patients treated with neoadjuvant radiation and/or chemotherapy are frequently encountered. These samples may show histologic features related to therapy including inflammation, ulceration, and epithelial atypia. In some cases, epithelial… read more here.
Keywords: p53 expression; expression; therapy related; p53 ... See more keywords
Bcl-2, p53, and Ki-67 expression in pterygium and normal conjunctiva and their relationship with pterygium recurrence
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Ophthalmology"
DOI: 10.1177/1120672120945903
Abstract: Purpose: Pterygium is a common lesion of the ocular surface, and its etiology and pathogenesis are still uncertain. This study aimed to investigate the role of apoptosis and proliferation in pterygium formation and recurrence. Materials… read more here.
Keywords: recurrence; tissue samples; pterygium; expression ... See more keywords