Constitutive Activation of the Tumor Suppressor p53 in Hepatocytes Paradoxically Promotes Non–Cell Autonomous Liver Carcinogenesis
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DOI: 10.1158/0008-5472.can-21-4390
Abstract: This study reveals that activation of p53 in hepatocytes promotes liver carcinogenesis derived from HPCs, which elucidates a paradoxical aspect of a tumor suppressor p53 and novel mechanism of liver carcinogenesis. read more here.
Keywords: p53 hepatocytes; tumor suppressor; suppressor p53; p53 ... See more keywords