Aberrant p53 immunostaining patterns in breast carcinoma of no special type strongly correlate with presence and type of TP53 mutations
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DOI: 10.1007/s00428-024-03897-3
Abstract: Recent studies have revealed an association between TP53 mutations and endocrine resistance in hormone receptor-positive, HER2-negative breast cancer (HR + HER2 −BC). Aberrant p53 immunostaining (IHC) patterns may provide a surrogate marker for TP53 mutations. Building upon… read more here.
Keywords: tp53 mutations; p53 immunostaining; type; aberrant p53 ... See more keywords
Quantitative p53 immunostaining aids in the detection of prevalent dysplasia
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Clinical Pathology"
DOI: 10.1136/jcp-2022-208721
Abstract: Aims The lack of accepted scoring criteria has precluded the use of p53 in routine practice. We evaluate the utility of automated quantitative p53 analysis in risk stratifying Barrett’s oesophagus (BE) patients using non-dysplastic BE… read more here.
Keywords: prevalent dysplasia; p53 immunostaining; p53; quantitative p53 ... See more keywords