Delineating functional mechanisms of the p53/p63/p73 family of transcription factors through identification of protein–protein interactions using interface mimicry
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DOI: 10.1002/mc.23405
Abstract: Members of the p53 family of transcription factors—p53, p63, and p73—share a high degree of homology; however, members can be activated in response to different stimuli, perform distinct (sometimes opposing) roles and are expressed in… read more here.
Keywords: family; p53 p63; transcription factors; p63 p73 ... See more keywords
p53, p63 and p73 in the wonderland of S. cerevisiae
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DOI: 10.18632/oncotarget.18506
Abstract: Since its discovery in 1979, p53 has been on the forefront of cancer research. It is considered a master gene of cancer suppression and is found mutated in around 50% of all human tumors. In… read more here.
Keywords: p53; p63 p73; p73 wonderland; p53 p63 ... See more keywords
p53 and p63 Proteoforms Derived from Alternative Splicing Possess Differential Seroreactivity in Colorectal Cancer with Distinct Diagnostic Ability from the Canonical Proteins
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DOI: 10.3390/cancers15072102
Abstract: Simple Summary The humoral immune response in cancer has been demonstrated to be useful for distinguishing patients from healthy individuals using serum or plasma. Our study aimed to assess whether p53 and p63 proteoforms derived… read more here.
Keywords: differential seroreactivity; p63 proteoforms; crc; p53 p63 ... See more keywords