Valosin-Containing Protein Stabilizes Mutant p53 to Promote Pancreatic Cancer Growth
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DOI: 10.1158/0008-5472.can-20-3855
Abstract: These findings identify valosin-containing protein (VCP) as a novel regulator of p53-R273H stability and suggest VCP as a potential target for development of pancreatic cancer therapy. Approximately 80% of human pancreatic ductal adenocarcinomas (PDAC) harbor… read more here.
Keywords: containing protein; p53 r273h; valosin containing; p53 ... See more keywords