The p53 protein induces stable miRNAs that have the potential to modify subsequent p53 responses.
Sign Up to like & getrecommendations! Published in 2017 at "Gene"
DOI: 10.1016/j.gene.2017.01.018
Abstract: The p53 tumour suppressor is a transcription factor that can increase the expression of mRNAs and microRNAs (miRNAs). HT29-tsp53 cells expressing a temperature sensitive variant of p53 have provided a useful model to rapidly and… read more here.
Keywords: p53 induced; induced mirnas; expression; p53 responsive ... See more keywords
GUARDIN is a p53-responsive long non-coding RNA that is essential for genomic stability
Sign Up to like & getrecommendations! Published in 2018 at "Nature Cell Biology"
DOI: 10.1038/s41556-018-0066-7
Abstract: The list of long non-coding RNAs (lncRNAs) involved in the p53 pathway of the DNA damage response is rapidly expanding, but whether lncRNAs have a role in maintaining the de novo structure of DNA is… read more here.
Keywords: guardin; long non; non coding; p53 responsive ... See more keywords