P53: Stability from the Ubiquitin–Proteasome System and Specific 26S Proteasome Inhibitors
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DOI: 10.1021/acsomega.1c04726
Abstract: Protein p53 is degraded by the 26S proteasome, a protein complex that breaks down cellular proteins. Degradation begins with activation of the protein ubiquitin (Ub) by the ubiquitin-activating E1 enzymes, ubiquitin-conjugating E2 enzymes, and ubiquitin… read more here.
Keywords: 26s proteasome; p53 stability; p53; ubiquitin proteasome ... See more keywords