Fish-Oil-Derived DHA-mediated Enhancement of Apoptosis in Acute Lymphoblastic Leukemia Cells is Associated with Accumulation of p53, Downregulation of Survivin, and Caspase-3 Activation
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DOI: 10.1080/01635581.2017.1247884
Abstract: ABSTRACT In acute lymphoblastic leukemia (ALL), resistance to chemotherapy is associated with inactivation of p53 and upregulation of survivin. Thus, targeting the p53 and survivin expression may provide an attractive strategy for ALL treatment. It… read more here.
Keywords: caspase activation; survivin; dha; p53 ... See more keywords
P53 and survivin expression in renal cell carcinoma
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DOI: 10.4103/ua.ua_91_22
Abstract: Objective: Mutation of p53 is detected in more than 50% of human cancers, expression of p53 has a potential prognostic value in patients with renal cell carcinoma (RCC). Survivin is a member of the inhibitor… read more here.
Keywords: cell; p53 survivin; expression; p53 ... See more keywords