p53 and TAp63 participate in the recombination-dependent pachytene arrest in mouse spermatocytes
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DOI: 10.1371/journal.pgen.1006845
Abstract: To protect germ cells from genomic instability, surveillance mechanisms ensure meiosis occurs properly. In mammals, spermatocytes that display recombination defects experience a so-called recombination-dependent arrest at the pachytene stage, which relies on the MRE11 complex—ATM—CHK2… read more here.
Keywords: p53 tap63; arrest; recombination dependent; pachytene ... See more keywords