Articles with "p53r172h" as a keyword



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The hot-spot p53R172H mutant promotes formation of giant spermatogonia triggered by DNA damage

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Published in 2017 at "Oncogene"

DOI: 10.1038/onc.2016.374

Abstract: Overexpression of mutant p53 is a common finding in most cancers but testicular tumours accumulate wild-type p53 (wtp53). In contrast to the accepted concept that p53 homozygous mutant mice do not accumulate mutant p53 in… read more here.

Keywords: dna damage; gsg; p53r172h; formation ... See more keywords