Pestones A and B from a Fungus Pestalotiopsis sp. Bound to Mutant p53 and Changed Its Conformation.
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DOI: 10.1021/acs.jnatprod.4c01440
Abstract: Oncogenic mutant p53 is one of the targets for cancer therapy, and the development of anticancer drugs that reactivate mutant p53 is a promising strategy. The extract of fungus Pestalotiopsis sp. changed mutant p53 to… read more here.
Keywords: p53r175h cells; saos p53r175h; p53; fungus pestalotiopsis ... See more keywords