STK40 inhibits trophoblast fusion by mediating COP1 ubiquitination to degrade P57Kip2
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Translational Medicine"
DOI: 10.1186/s12967-024-05360-y
Abstract: The syncytiotrophoblast (SCT) layer in the placenta serves as a crucial physical barrier separating maternal-fetal circulation, facilitating essential signal and substance exchange between the mother and fetus. Any abnormalities in its formation or function can… read more here.
Keywords: trophoblast fusion; p57kip2; fusion; stk40 ... See more keywords
High Dosage Lithium Treatment Induces DNA Damage and p57Kip2 Decrease
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DOI: 10.3390/ijms21031169
Abstract: Lithium salt is the first-line therapeutic option for bipolar disorder and has been proposed as a potential antitumoral drug. The effects of LiCl treatment were investigated in SH-SY5Y, a human neuroblastoma cell line and an… read more here.
Keywords: dna damage; damage p57kip2; treatment; lithium ... See more keywords