p62 bodies: Phase separation, NRF2 activation, and selective autophagic degradation
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DOI: 10.1002/iub.2689
Abstract: When p62/Sequestosome‐1 binds to a ubiquitinated protein, it undergoes liquid–liquid phase separation (LLPS) and forms a membraneless organelle, p62 body. There are two major physiological functions of the p62 body. One is effective autophagic degradation… read more here.
Keywords: p62 body; degradation; phase separation; autophagic degradation ... See more keywords