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Sorafenib-Induced Autophagy Promotes Glycolysis by Upregulating the p62/HDAC6/HSP90 Axis in Hepatocellular Carcinoma Cells

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Published in 2021 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2021.788667

Abstract: Sorafenib has attracted much attention as the first drug approved by the FDA for the treatment of advanced hepatocellular carcinoma (HCC). Because of the drug tolerance, the overall outcomes were far from satisfactory. Current studies… read more here.

Keywords: induced autophagy; hsp90; hepatocellular carcinoma; sorafenib induced ... See more keywords