Targeting YAP‐p62 signaling axis suppresses the EGFR‐TKI‐resistant lung adenocarcinoma
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DOI: 10.1002/cam4.3734
Abstract: Despite the progress of advanced target therapeutic agents and immune checkpoint inhibitors, EGFR‐TKI resistance is still one of the biggest obstacles in treating lung cancer. Clinical studies with autophagy inhibitors are actively underway to overcome… read more here.
Keywords: egfr tki; tki; targeting yap; p62 signaling ... See more keywords
Andrographolide Protects PC12 Cells Against β-Amyloid-Induced Autophagy-Associated Cell Death Through Activation of the Nrf2-Mediated p62 Signaling Pathway
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DOI: 10.3390/ijms19092844
Abstract: Recent studies mentioned that Andrographolide (Andro), the main bioactive component of traditional Chinese medicine Andrographis paniculata, may be a potential natural product for treating Alzheimer's disease, but the underlining mechanism remains to be discovered. In… read more here.
Keywords: pc12 cells; p62 signaling; signaling pathway; nrf2 mediated ... See more keywords