Regulated proteolysis of p62/SQSTM1 enables differential control of autophagy and nutrient sensing
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DOI: 10.1126/scisignal.aat6903
Abstract: A p62 fragment generated by caspase-8 regulates responses to nutrient availability, rather than autophagy. Cleaving a different function for p62 The scaffold protein p62 has a critical role in autophagy, the regulated degradation of proteins… read more here.
Keywords: caspase; p62trm; regulated proteolysis; p62 ... See more keywords