SPARCL1 targeting BST2 mediates meniscal inflammation and catabolic dysfunction by activating the NF-κB/P65 pathway.
Sign Up to like & getrecommendations! Published in 2025 at "Rheumatology"
DOI: 10.1093/rheumatology/keaf345
Abstract: OBJECTIVES Meniscus injury is one of the most common musculoskeletal injuries, and its pathogenesis is associated with age, mechanical stress, and inflammatory injury. However, the mechanism of meniscal degeneration remains unclear, and this study aimed… read more here.
Keywords: sparcl1; degeneration; meniscus; p65 pathway ... See more keywords
Qishen Granule (QSG) Inhibits Monocytes Released From the Spleen and Protect Myocardial Function via the TLR4-MyD88-NF-κB p65 Pathway in Heart Failure Mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.850187
Abstract: Preliminary clinical and basic researches have proved that Qishen granule (QSG) is an effective prescription for treating heart failure (HF) in China, with a characteristic of regulating the ratio of M1/M2 macrophage in the myocardium.… read more here.
Keywords: tlr4 myd88; myd88 p65; p65 pathway; qsg ... See more keywords