Relative domain orientation of the L289K HIV‐1 reverse transcriptase monomer
Sign Up to like & getrecommendations! Published in 2022 at "Protein Science"
DOI: 10.1002/pro.4307
Abstract: HIV‐1 reverse transcriptase (RT) is a heterodimer comprised p66 and p51 subunits (p66/p51). Several single amino acid substitutions in RT, including L289K, decrease p66/p51 dimer affinity, and reduce enzymatic functioning. Here, small‐angle X‐ray scattering (SAXS)… read more here.
Keywords: reverse transcriptase; hiv reverse; domain; p66 p51 ... See more keywords