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p66Shc promotes HCC progression in the tumor microenvironment via STAT3 signaling.

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1 Published in 2019 at "Experimental cell research"

DOI: 10.1016/j.yexcr.2019.111550

Abstract: The development of hepatocellular carcinoma (HCC) is strongly associated with chronic inflammation. p66Shc is an oxidase previously shown to promote androgen-independent cell growth through generation of reactive oxygen species. However, the importance and biologic functions… read more here.

Keywords: hcc; promotes hcc; stat3; p66shc promotes ... See more keywords