p67phox binds to a newly identified site in Nox2 following the disengagement of an intramolecular bond—Canaan sighted?
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.4a1219-607r
Abstract: Activation of the phagocyte NADPH oxidase involves a conformational change in Nox2. The effector in this process is p67phox and there is evidence for a change in the configuration of p67phox being required for binding… read more here.
Keywords: intramolecular bond; nox2; site; p67phox ... See more keywords
Upregulation of p67phox in response to ischemia/reperfusion is cardioprotective by increasing ZIP2 expression via STAT3
Sign Up to like & getrecommendations! Published in 2022 at "Free Radical Research"
DOI: 10.1080/10715762.2022.2052057
Abstract: Abstract While the zinc transporter ZIP2 (Slc39a2) is upregulated via STAT3 as an adaptive response to protect the heart from ischemia/reperfusion (I/R) injury, the precise mechanism underlying its upregulation remains unclear. The purpose of this… read more here.
Keywords: upregulation; reperfusion; zip2 expression; expression ... See more keywords