LincRNA‐p21 knockdown enhances radiosensitivity of hypoxic tumor cells by reducing autophagy through HIF‐1/Akt/mTOR/P70S6K pathway
Sign Up to like & getrecommendations! Published in 2017 at "Experimental Cell Research"
DOI: 10.1016/j.yexcr.2017.06.016
Abstract: ABSTRACT Hypoxic conditions are common in solid tumors and have a significant effect on tumor progression, therapeutic and prognosis. Long noncoding RNAs (lncRNAs) are longer than 200 nucleotides and cannot be translated into proteins, which… read more here.
Keywords: p70s6k pathway; lincrna p21; p21; akt mtor ... See more keywords
Phosphoproteomic Analysis of Neonatal Regenerative Myocardium Revealed Important Roles of CHK1 via Activating mTORC1/P70S6K Pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Circulation"
DOI: 10.1161/circulationaha.119.040747
Abstract: Background: In mammalian, regenerative therapy after myocardial infarction (MI) is hampered by the limited regenerative capacity of adult heart, while a transient regenerative capacity is maintained in the neonatal heart. Systemic phosphorylation signaling analysis on… read more here.
Keywords: chk1; p70s6k pathway; myocardium; regeneration ... See more keywords
Albiflorin alleviates sepsis-induced acute liver injury through mTOR/p70S6K pathway.
Sign Up to like & getrecommendations! Published in 2023 at "Current molecular medicine"
DOI: 10.2174/1566524023666230309124004
Abstract: BACKGROUND Sepsis often induces hepatic dysfunction and inflammation, accounting for a significant increase in the incidence and mortality rates. To this end, albiflorin (AF) has garnered enormous interest due to its potent anti-inflammatory activity. However,… read more here.
Keywords: sepsis; injury; mtor p70s6k; p70s6k pathway ... See more keywords