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   Articles with "p75" as a keyword



Identification and application of p75 neurotrophin receptor-expressing human trabecular meshwork progenitor cells.

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recommendations! Published in 2019 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2019.04.178

Abstract: The trabecular meshwork (TM) is a tissue that originates from the neural crest via the periocular mesenchyme and plays a role in draining water and maintaining intraocular pressure (IOP). Damage to the TM is associated… read more here.

Keywords: neurotrophin receptor; trabecular meshwork; progenitor cells; p75 ... See more keywords

Targeted editing of the PSIP1 gene encoding LEDGF/p75 protects cells against HIV infection

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recommendations! Published in 2019 at "Scientific Reports"

DOI: 10.1038/s41598-019-38718-0

Abstract: To fulfill a productive infection cycle the human immunodeficiency virus (HIV) relies on host-cell factors. Interference with these co-factors holds great promise in protecting cells against HIV infection. LEDGF/p75, encoded by the PSIP1 gene, is… read more here.

Keywords: ledgf p75; hiv infection; p75; cells hiv ... See more keywords

c-Jun N-terminal kinase (JNK)-dependent internalization and Rab5-dependent endocytic sorting mediate long-distance retrograde neuronal death induced by axonal BDNF-p75 signaling

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recommendations! Published in 2019 at "Scientific Reports"

DOI: 10.1038/s41598-019-42420-6

Abstract: During the development of the sympathetic nervous system, signals from tropomyosin-related kinase receptors (Trks) and p75 neurotrophin receptors (p75) compete to regulate survival and connectivity. During this process, nerve growth factor (NGF)- TrkA signaling in… read more here.

Keywords: rab5; death; neuronal death; p75 signaling ... See more keywords

Cell non-autonomous requirement of p75 in the development of geniculate oral sensory neurons

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recommendations! Published in 2020 at "Scientific Reports"

DOI: 10.1038/s41598-020-78816-y

Abstract: During development of the peripheral taste system, oral sensory neurons of the geniculate ganglion project via the chorda tympani nerve to innervate taste buds in fungiform papillae. Germline deletion of the p75 neurotrophin receptor causes… read more here.

Keywords: taste; p75; cre p75fx; sensory neurons ... See more keywords

PSIP1/p75 promotes tumorigenicity in breast cancer cells by promoting the transcription of cell cycle genes

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recommendations! Published in 2017 at "Carcinogenesis"

DOI: 10.1093/carcin/bgx062

Abstract: Breast cancer (BC) is a highly heterogeneous disease, both at the pathological and molecular level, and several chromatin-associated proteins play crucial roles in BC initiation and progression. Here, we demonstrate the role of PSIP1 (PC4… read more here.

Keywords: psip1 p75; p75; cell cycle; tumorigenicity ... See more keywords

Carbon dioxide rebreathing induced by crib bumpers and mesh liners using an infant manikin

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recommendations! Published in 2019 at "BMJ Paediatrics Open"

DOI: 10.1136/bmjpo-2018-000374

Abstract: Objectives Quantify impaired respiration in currently marketed crib bumpers (CBs), mesh liners (MLs) and alternative products (ALTs) used to attenuate the interaction between the baby and the crib sides and elucidate the relationship between impaired… read more here.

Keywords: p25; co2rb; p75; permeability ... See more keywords

NGF/TRKA Promotes ADAM17-Dependent Cleavage of P75 in Ovarian Cells: Elucidating a Pro-Tumoral Mechanism

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recommendations! Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23042124

Abstract: Nerve growth factor (NGF) and its high-affinity receptor TRKA are overexpressed in epithelial ovarian cancer (EOC) displaying a crucial role in the disease progression. Otherwise, NGF interacts with its low-affinity receptor P75, activating pro-apoptotic pathways.… read more here.

Keywords: cleavage p75; p75 ovarian; trka; p75 ... See more keywords

Generation of a Live-Attenuated Strain of Chikungunya Virus from an Indian Isolate for Vaccine Development

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recommendations! Published in 2022 at "Vaccines"

DOI: 10.3390/vaccines10111939

Abstract: Chikungunya virus (CHIKV) re-emergence in the last decade has resulted in explosive epidemics. Along with the classical symptoms of fever and debilitating arthralgia, there were occurrences of unusual clinical presentations such as neurovirulence and mortality.… read more here.

Keywords: chikungunya virus; vaccine development; strain; p75 ... See more keywords