Evaluation of a flavonoid library for inhibition of interaction of HIV-1 integrase with human LEDGF/p75 towards a structure–activity relationship
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DOI: 10.1080/07853890.2022.2081869
Abstract: Abstract Background: Proteinśprotein interaction (PPI) between lens epithelium-derived growth factor (LEDGF/p75) and human immunodeficiency virus (HIV) integrase (IN) becomes an attractive target for anti-HIV drug development. Methods: The blockade of this interaction by small molecules… read more here.
Keywords: p75 interaction; interaction; hiv integrase; ledgf p75 ... See more keywords