Proteolytic Release of the p75NTR Intracellular Domain by ADAM10 Promotes Metastasis and Resistance to Anoikis.
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DOI: 10.1158/0008-5472.can-17-2789
Abstract: Resistance to anoikis allows cancer cells to survive during systemic circulation; however, the mechanism underlying anoikis resistance remains unclear. Here we show that A disintegrin and metalloprotease 10 (ADAM10)-mediated cleavage of p75 neurotrophin receptor (p75NTR)… read more here.
Keywords: p75ntr; anoikis; p75ntr icd; resistance ... See more keywords