Pro-BDNF Contributes to Hypoxia/Reoxygenation Injury in Myocardial Microvascular Endothelial Cells: Roles of Receptors p75NTR and Sortilin and Activation of JNK and Caspase 3
Sign Up to like & getrecommendations! Published in 2018 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2018/3091424
Abstract: The aim of this study was to identify the role of the precursor of the brain-derived neurotrophic factor (pro-BDNF) in myocardial hypoxia/reoxygenation injury (H/R) and to address the underlying mechanisms. For this purpose, myocardial microvascular… read more here.
Keywords: pro bdnf; p75ntr sortilin; jnk caspase; injury ... See more keywords
A Novel Neuroprotective Mechanism for Lithium That Prevents Association of the p75NTR-Sortilin Receptor Complex and Attenuates proNGF-Induced Neuronal Death In Vitro and In Vivo
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DOI: 10.1523/eneuro.0257-17.2017
Abstract: Abstract Neurotrophins play critical roles in the survival, maintenance and death of neurons. In particular, proneurotrophins have been shown to mediate cell death following brain injury induced by status epilepticus (SE) in rats. Previous studies… read more here.
Keywords: death; p75ntr; receptor complex; sortilin receptor ... See more keywords