C-SH2 point mutation converts p85β regulatory subunit of phosphoinositide 3-kinase to an anti-aging gene
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DOI: 10.1038/s41598-019-48157-6
Abstract: Insulin interacts with the insulin receptor, and the activated receptor promotes activity of the phosphoinositide-3 kinase (PI3K) enzyme. A decrease in insulin or insulin-like growth factor 1 (IGF-1) signaling increases the lifespan in mammalian species.… read more here.
Keywords: point mutation; p85 regulatory; phosphoinositide kinase; gene ... See more keywords