Articles with "pab mmae" as a keyword



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Monomethyl auristatin E-conjugated anti-EGFR antibody inhibits the growth of human EGFR-positive non-small cell lung cancer

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Published in 2019 at "Cancer Chemotherapy and Pharmacology"

DOI: 10.1007/s00280-019-03848-9

Abstract: PurposeEpidermal growth factor receptor (EGFR) is highly expressed on non-small cell lung cancers (NSCLC) and a valuable therapeutic target. This study aimed at producing and characterizing monomethyl auristatin E (MMAE)-conjugated anti-EGFR antibody as a novel… read more here.

Keywords: rc68 pab; mmae; egfr; pab mmae ... See more keywords