N-Propargyl Caffeamide (PACA) Ameliorates Dopaminergic Neuronal Loss and Motor Dysfunctions in MPTP Mouse Model of Parkinson’s Disease and in MPP+-Induced Neurons via Promoting the Conversion of proNGF to NGF
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Neurobiology"
DOI: 10.1007/s12035-017-0486-6
Abstract: AbstractInsufficient production of nerve growth factor (NGF) is implicated in Parkinson’s disease (PD). We recently discovered that caffeic acid derivative N-propargyl caffeamide (PACA) not only potentiated NGF-induced neurite outgrowth but also attenuated 6-hydroxydopamine neurotoxicity in… read more here.
Keywords: ngf levels; paca; propargyl caffeamide; motor ... See more keywords
Measurement of urinary kininogen (KNG) fragments as a noninvasive tool for early diagnosis of pancreatic cancer (PaCa).
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.4_suppl.209
Abstract: 209 Background: There is a clear need to identify a non-invasive biomarker for early diagnosis of PaCa, in order to improve the overall survival of PaCa patients. Secretion of large amounts of proteases is a… read more here.
Keywords: paca patients; kng fragments; paca; early diagnosis ... See more keywords
Pancreatic cancer detection using EpiDetect signatures in plasma-derived cell free DNA in high-risk patients with new onset diabetes.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2021.39.15_suppl.e16265
Abstract: e16265 Background: Pancreatic cancer (PaCa) is the third leading cause of cancer death in the United States despite its low incidence rate, owing to a 5-year survival rate of 10%. It is often asymptomatic in… read more here.
Keywords: paca patients; cancer; plasma derived; paca ... See more keywords
Ping-Pong—Tumor and Host in Pancreatic Cancer Progression
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2019.01359
Abstract: Metastasis is the main cause of high pancreatic cancer (PaCa) mortality and trials dampening PaCa mortality rates are not satisfying. Tumor progression is driven by the crosstalk between tumor cells, predominantly cancer-initiating cells (CIC), and… read more here.
Keywords: pancreatic cancer; paca; cancer; progression ... See more keywords
NEUROD1 predicts better prognosis in pancreatic cancer revealed by a TILs-based prognostic signature
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1025921
Abstract: It has been well-defined that tumor-infiltrating lymphocytes (TILs) play critical roles in pancreatic cancer (PaCa) progression. This research aimed to comprehensively explore the composition of TILs in PaCa and their potential clinical significance. A total… read more here.
Keywords: paca; pancreatic cancer; signature; based prognostic ... See more keywords
Analyzing the Mechanical Properties of Free-Standing PACA Thin Films Using Microindentation Technique
Sign Up to like & getrecommendations! Published in 2022 at "Polymers"
DOI: 10.3390/polym14224863
Abstract: Assessing the mechanical properties of materials is of fundamental relevance for their rational usage, but can be challenging with standard tensile testing for highly brittle polymers used, e.g., as coatings. Here, a procedure for the… read more here.
Keywords: paca; free standing; using microindentation; mechanical properties ... See more keywords
The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Morphology"
DOI: 10.4067/s0717-95022020000601525
Abstract: Department of Surgery School of Veterinary Medicine and Animal Science University of Sao Paulo (FMVZ-USP), Av. Prof. Dr. Orlando Marques de Paiva, 87, Cidade Universitaria read more here.
Keywords: paca; morphology; morphology paca; cuniculus paca ... See more keywords