Two new pregnane alkaloids from Pachysandra terminalis Sieb. et Zucc.
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DOI: 10.1080/14786419.2020.1744143
Abstract: Two new pregnane alkaloids, (20S)-20α-cinnamoylamino-3β-dimethylamino-5-en-pregnane (1) and (20S)-20α-cinnamoylamino-3β-dimethylamino-pregnane (2), and four known alkaloids (+)-(20S)-20-(dimethylamino)-3-(3'R-isopropyl)-lactam-5α-pregn-2-en-4-one (3), axillaridine A (4), pachysamine M (5) and 20α-dimethylamino-16β-hydroxy-3β-senecioylamino-pregn-5-ene (6) were obtained from the whole herb of Pachysandra terminalis Sieb. et… read more here.
Keywords: two new; pregnane; pregnane alkaloids; pachysandra terminalis ... See more keywords
The Alkaloid-Enriched Fraction of Pachysandra terminalis (Buxaceae) Shows Prominent Activity against Trypanosoma brucei rhodesiense
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DOI: 10.3390/molecules26030591
Abstract: In the course of our studies on antiprotozoal natural products and following our recent discovery that certain aminosteroids and aminocycloartanoid compounds from Holarrhena africana A. DC. (Apocynaceae) and Buxus sempervirens L. (Buxaceae), respectively, are strong… read more here.
Keywords: brucei rhodesiense; pachysandra terminalis; trypanosoma brucei; activity trypanosoma ... See more keywords