High resolution structure of hexameric herpesvirus DNA-packaging motor elucidates revolving mechanism and ends 20-year fervent debate
Sign Up to like & getrecommendations! Published in 2020 at "Protein & Cell"
DOI: 10.1007/s13238-020-00714-w
Abstract: In this issue of the Protein & Cell Journal, a research team (from Institute of Biophysics, Chinese Academy of Sciences) led by professors Xiangxi Wang and Zihe Rao report the high-resolution structural and physical properties… read more here.
Keywords: dna packaging; herpesvirus; packaging motor; dna ... See more keywords
Nano-channel of viral DNA packaging motor as single pore to differentiate peptides with single amino acid difference.
Sign Up to like & getrecommendations! Published in 2018 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2018.08.005
Abstract: Detection, differentiation, mapping, and sequencing of proteins are important in proteomics for the assessment of cell development such as protein methylation or phosphorylation as well as the diagnosis of diseases including metabolic disorder, mental illness,… read more here.
Keywords: amino; packaging motor; dna; peptides single ... See more keywords
Atomistic basis of force generation, translocation, and coordination in a viral genome packaging motor
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkab372
Abstract: Abstract Double-stranded DNA viruses package their genomes into pre-assembled capsids using virally-encoded ASCE ATPase ring motors. We present the first atomic-resolution crystal structure of a multimeric ring form of a viral dsDNA packaging motor, the… read more here.
Keywords: packaging motor; atomistic basis; basis force; motor ... See more keywords
A phage satellite manipulates the viral DNA packaging motor to inhibit phage and promote satellite spread
Sign Up to like & getrecommendations! Published in 2024 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkae675
Abstract: Abstract ICP1, a lytic bacteriophage of Vibrio cholerae, is parasitized by phage satellites, PLEs, which hijack ICP1 proteins for their own horizontal spread. PLEs' dependence on ICP1’s DNA replication machinery and virion components results in… read more here.
Keywords: satellite; phage; ple; packaging motor ... See more keywords