Response to neoadjuvant paclitaxel predicts survival in anaplastic thyroid carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5219
Abstract: The clinical utilities of paclitaxel in anaplastic thyroid carcinoma (ATC) have been reported. The current study investigated the outcomes in ATC patients treated by paclitaxel as neoadjuvant setting. Furthermore, the prognostic factor for overall survival… read more here.
Keywords: thyroid carcinoma; response paclitaxel; paclitaxel; response ... See more keywords
Drug‐eluting stent, drug eluting balloon controversy in peripheral artery disease; what is the verdict?
Sign Up to like & getrecommendations! Published in 2020 at "Catheterization and Cardiovascular Interventions"
DOI: 10.1002/ccd.29355
Abstract: Endovascular therapy offers a less invasive treatment option compared to surgery, and therefore, has become the therapy of choice in many patients with peripheral artery disease (PAD). Restenosis due to neointimal hyperplasia; however, is a… read more here.
Keywords: drug eluting; analysis; disease; mortality ... See more keywords
Phase III randomized, double‐blind study of paclitaxel with and without everolimus in patients with advanced gastric or esophagogastric junction carcinoma who have progressed after therapy with a fluoropyrimidine/platinum‐containing regimen (RADPAC)
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Cancer"
DOI: 10.1002/ijc.33025
Abstract: The RADPAC trial evaluated paclitaxel with everolimus in patients with advanced gastroesophageal cancer (GEC) who have progressed after therapy with a fluoropyrimidine/platinum‐containing regimen. Patients were randomly assigned to receive paclitaxel (80 mg/m2) on day 1, 8… read more here.
Keywords: patients advanced; therapy fluoropyrimidine; therapy; progressed therapy ... See more keywords
Antagonistic anticancer effect of paclitaxel and digoxin combination
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28583
Abstract: Despite the growing interest in the antitumor effect of cardiotonic steroids, combination treatments with well‐established chemotherapy drugs like paclitaxel have been rarely investigated. Moreover, paclitaxel has been suggested as a Na+/K+‐ATPase inhibitor. Here we investigated… read more here.
Keywords: combination; paclitaxel digoxin; effect; effect paclitaxel ... See more keywords
Paclitaxel-coated stents to prevent hyperplastic proliferation of ureteral tissue: from in vitro to in vivo
Sign Up to like & getrecommendations! Published in 2018 at "Urolithiasis"
DOI: 10.1007/s00240-018-1081-7
Abstract: Ureteric stents have become an indispensable tool in the armamentarium of every urologist. However, they carry their own morbidity resulting mostly from infectious or abacterial fouling and biofilm formation, and/or urothelial hyperplastic reaction. All of… read more here.
Keywords: coated stents; proliferation ureteral; paclitaxel coated; hyperplastic proliferation ... See more keywords
Lapatinib in combination with paclitaxel plays synergistic antitumor effects on esophageal squamous cancer
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-018-3627-3
Abstract: PurposePaclitaxel-based chemoradiotherapy was proven to be efficacious in treating patients with advanced esophageal cancer. However, the toxicity and the development of resistance limited its anticancer efficiency. The present study was to evaluate the antitumor effects… read more here.
Keywords: combination; squamous cancer; antitumor; cancer ... See more keywords
Nab-paclitaxel plus S-1 as first-line followed by S-1 maintenance for advanced pancreatic adenocarcinoma: a single-arm phase II trial
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-018-3650-4
Abstract: PurposeWe conducted a single-arm prospective phase II study to determine the efficacy and safety of the first-line treatment of advanced pancreatic cancer with nab-paclitaxel and S-1 followed by S-1 maintenance therapy.MethodsNab-paclitaxel was administered intravenously on… read more here.
Keywords: first line; maintenance; advanced pancreatic; single arm ... See more keywords
Nanoparticle albumin-bound paclitaxel: a big nano for the treatment of gastric cancer
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-019-03887-2
Abstract: Gastric cancer (GC) is the third cause of cancer-related death worldwide. Patients with unresectable GC can be treated with chemotherapy such as paclitaxel, which is a microtubule stabilizer. The use of nanoparticle albumin-bound paclitaxel (nab-ptx)… read more here.
Keywords: nanoparticle albumin; gastric cancer; bound paclitaxel; cancer ... See more keywords
Beneficial effects of Gelsemium-based treatment against paclitaxel-induced painful symptoms
Sign Up to like & getrecommendations! Published in 2018 at "Neurological Sciences"
DOI: 10.1007/s10072-018-3575-z
Abstract: Chemotherapeutic drugs induce various side effects including painful peripheral neuropathy that represents a major concern. The widely used anticancer drug paclitaxel causes neurological side effects such as burning pain, allodynia, and hyperalgesia. Neuroprotective substances that… read more here.
Keywords: paclitaxel induced; treatment; based treatment; allodynia hyperalgesia ... See more keywords
Randomized phase II trial of carboplatin + nab-paclitaxel versus cisplatin + gemcitabine for chemotherapy-naïve squamous cell carcinoma: North Japan lung cancer study group 1302
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Clinical Oncology"
DOI: 10.1007/s10147-020-01828-1
Abstract: A subset analysis of the CA031 trial showed significant improvement in the overall response rate after administration of carboplatin plus weekly albumin-bound paclitaxel compared to carboplatin plus paclitaxel for squamous cell carcinoma of the lung… read more here.
Keywords: cnp; cell carcinoma; squamous cell; cisplatin ... See more keywords
Phase 2 study of bevacizumab plus carboplatin/nab-paclitaxel followed by bevacizumab plus nab‐paclitaxel for non‐squamous non‐small cell lung cancer with malignant pleural effusion
Sign Up to like & getrecommendations! Published in 2021 at "Investigational New Drugs"
DOI: 10.1007/s10637-021-01076-8
Abstract: Objectives Vascular endothelial growth factor plays an important role in the pathogenesis of malignant pleural effusion (MPE). We previously showed the efficacy of bevacizumab (Bev) plus carboplatin (CBDCA)/paclitaxel (PTX) in the treatment of non-small lung… read more here.
Keywords: nab paclitaxel; ptx; study; malignant pleural ... See more keywords