Response to neoadjuvant paclitaxel predicts survival in anaplastic thyroid carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5219
Abstract: The clinical utilities of paclitaxel in anaplastic thyroid carcinoma (ATC) have been reported. The current study investigated the outcomes in ATC patients treated by paclitaxel as neoadjuvant setting. Furthermore, the prognostic factor for overall survival… read more here.
Keywords: thyroid carcinoma; response paclitaxel; paclitaxel; response ... See more keywords
Drug‐eluting stent, drug eluting balloon controversy in peripheral artery disease; what is the verdict?
Sign Up to like & getrecommendations! Published in 2020 at "Catheterization and Cardiovascular Interventions"
DOI: 10.1002/ccd.29355
Abstract: Endovascular therapy offers a less invasive treatment option compared to surgery, and therefore, has become the therapy of choice in many patients with peripheral artery disease (PAD). Restenosis due to neointimal hyperplasia; however, is a… read more here.
Keywords: drug eluting; analysis; disease; mortality ... See more keywords
Functionalizing Sgc8‐Paclitaxel Conjugates with F‐Base Modifications: Targeted Drug Delivery with Optimized Cardiac Safety
Sign Up to like & getrecommendations! Published in 2024 at "ChemMedChem"
DOI: 10.1002/cmdc.202400112
Abstract: Recent advancements in cancer treatment have improved patient prognoses, but chemotherapy induced cardiotoxicity remains a prevalent concern. This study explores the potential of F‐base‐modified aptamers for targeted drug delivery, focusing on their impact on cardiotoxicity.… read more here.
Keywords: paclitaxel; sgc8 f23; drug delivery; drug ... See more keywords
Phase III randomized, double‐blind study of paclitaxel with and without everolimus in patients with advanced gastric or esophagogastric junction carcinoma who have progressed after therapy with a fluoropyrimidine/platinum‐containing regimen (RADPAC)
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Cancer"
DOI: 10.1002/ijc.33025
Abstract: The RADPAC trial evaluated paclitaxel with everolimus in patients with advanced gastroesophageal cancer (GEC) who have progressed after therapy with a fluoropyrimidine/platinum‐containing regimen. Patients were randomly assigned to receive paclitaxel (80 mg/m2) on day 1, 8… read more here.
Keywords: patients advanced; therapy fluoropyrimidine; therapy; progressed therapy ... See more keywords
Tislelizumab combined with nab‐paclitaxel and cisplatin as the more effective chemoimmunotherapy strategy in the neoadjuvant treatment of locally advanced thoracic esophageal squamous cell carcinoma: A prospective, two‐cohort, phase 2 trial
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Cancer"
DOI: 10.1002/ijc.35261
Abstract: This prospective, two‐cohort phase 2 trial with random allocation was conducted to evaluate the safety and efficacy of neoadjuvant tislelizumab combined with nab‐paclitaxel/paclitaxel and cisplatin (TP) in patients with esophageal squamous cell carcinoma (ESCC). Patients… read more here.
Keywords: cohort; paclitaxel; prospective two; nab paclitaxel ... See more keywords
Antagonistic anticancer effect of paclitaxel and digoxin combination
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28583
Abstract: Despite the growing interest in the antitumor effect of cardiotonic steroids, combination treatments with well‐established chemotherapy drugs like paclitaxel have been rarely investigated. Moreover, paclitaxel has been suggested as a Na+/K+‐ATPase inhibitor. Here we investigated… read more here.
Keywords: combination; paclitaxel digoxin; effect; effect paclitaxel ... See more keywords
Supramolecular Micelleplex Co-Delivers Bcl-2 siRNA and Paclitaxel for Synergistic Chemo-Gene Cancer Therapy.
Sign Up to like & getrecommendations! Published in 2025 at "Small methods"
DOI: 10.1002/smtd.202500760
Abstract: Combined chemotherapy (CT) and gene therapy (GT) represent a reliable modality toward drug‐resistant tumor treatment. Yet, physical‐chemical differences between chemodrugs and nucleic acids often hinder the construction of feasible delivery systems with synergistic activity. Herein,… read more here.
Keywords: paclitaxel; therapy; ptx; tumor ... See more keywords
Paclitaxel-coated stents to prevent hyperplastic proliferation of ureteral tissue: from in vitro to in vivo
Sign Up to like & getrecommendations! Published in 2018 at "Urolithiasis"
DOI: 10.1007/s00240-018-1081-7
Abstract: Ureteric stents have become an indispensable tool in the armamentarium of every urologist. However, they carry their own morbidity resulting mostly from infectious or abacterial fouling and biofilm formation, and/or urothelial hyperplastic reaction. All of… read more here.
Keywords: coated stents; proliferation ureteral; paclitaxel coated; hyperplastic proliferation ... See more keywords
Lapatinib in combination with paclitaxel plays synergistic antitumor effects on esophageal squamous cancer
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-018-3627-3
Abstract: PurposePaclitaxel-based chemoradiotherapy was proven to be efficacious in treating patients with advanced esophageal cancer. However, the toxicity and the development of resistance limited its anticancer efficiency. The present study was to evaluate the antitumor effects… read more here.
Keywords: combination; squamous cancer; antitumor; cancer ... See more keywords
Nab-paclitaxel plus S-1 as first-line followed by S-1 maintenance for advanced pancreatic adenocarcinoma: a single-arm phase II trial
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-018-3650-4
Abstract: PurposeWe conducted a single-arm prospective phase II study to determine the efficacy and safety of the first-line treatment of advanced pancreatic cancer with nab-paclitaxel and S-1 followed by S-1 maintenance therapy.MethodsNab-paclitaxel was administered intravenously on… read more here.
Keywords: first line; maintenance; advanced pancreatic; single arm ... See more keywords
Nanoparticle albumin-bound paclitaxel: a big nano for the treatment of gastric cancer
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-019-03887-2
Abstract: Gastric cancer (GC) is the third cause of cancer-related death worldwide. Patients with unresectable GC can be treated with chemotherapy such as paclitaxel, which is a microtubule stabilizer. The use of nanoparticle albumin-bound paclitaxel (nab-ptx)… read more here.
Keywords: nanoparticle albumin; gastric cancer; bound paclitaxel; cancer ... See more keywords