Synthesis and Biological Evaluation of Paclitaxel-aminoguanidine Conjugates for Suppressing Breast Cancer.
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DOI: 10.2174/1570179420666230327090545
Abstract: BACKGROUND A combination of paclitaxel with antineoplastic agents or paclitaxel alone was used clinically for the treatment of metastatic breast cancer. However, paclitaxel has poor water solubility and limited effect on some metastatic breast cancers.… read more here.
Keywords: aminoguanidine; breast; paclitaxel aminoguanidine; cancer ... See more keywords