A Facile and Novel Approach to Manufacture Paclitaxel-Loaded Proliposome Tablet Formulations of Micro or Nano Vesicles for Nebulization
Sign Up to like & getrecommendations! Published in 2020 at "Pharmaceutical Research"
DOI: 10.1007/s11095-020-02840-w
Abstract: Purpose The aim of this study was to develop novel paclitaxel-loaded proliposome tablet formulations for pulmonary drug delivery. Method Proliposome powder formulations (i.e. F1 – F27) were prepared employing Lactose monohydrate (LMH), Microcrystalline cellulose (MCC)… read more here.
Keywords: nebulization; tablet formulations; paclitaxel loaded; proliposome tablet ... See more keywords
Controllable Subtractive Nanoimprint Lithography for Precisely Fabricating Paclitaxel-loaded PLGA Nanocylinders to Enhance Anticancer Efficacy.
Sign Up to like & getrecommendations! Published in 2020 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.9b21346
Abstract: Nanoimprint lithography presents a new strategy for preparing uniform nanostructures with predefined sizes and shapes, and has the potential for developing nanosized drug delivery systems. However, current nanoimprint lithography is a type of additive nanofabrication… read more here.
Keywords: loaded plga; paclitaxel loaded; nanoimprint; nanoimprint lithography ... See more keywords
Evaluation of novel paclitaxel-loaded NO-donating polymeric micelles for an improved therapy for gastroenteric tumor
Sign Up to like & getrecommendations! Published in 2021 at "New Journal of Chemistry"
DOI: 10.1039/d1nj00979f
Abstract: A NO-releasing polymer (mPEG-PLA-NO) is developed as a micellar nanoparticle delivery system for the carrier of antitumor drug paclitaxel. read more here.
Keywords: evaluation novel; novel paclitaxel; paclitaxel loaded; donating polymeric ... See more keywords
Abstract 4662: Comparing 2D and 3D culture models for in vitro therapeutic screening of paclitaxel loaded micelles co-administered with iRGD peptide
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-4662
Abstract: Clinical efficacy of paclitaxel, a potent chemotherapeutic agent, is limited by its nonspecificity that leads to toxic side effects. Polymeric micellar formulations of paclitaxel were designed with the long term goals of decreasing toxicity by… read more here.
Keywords: irgd peptide; paclitaxel loaded; culture models; culture ... See more keywords
Design and Characterization of Paclitaxel-Loaded Polymeric Nanoparticles Decorated With Trastuzumab for the Effective Treatment of Breast Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.855294
Abstract: The aim of the study was to design and formulate an antibody-mediated targeted, biodegradable polymeric drug delivery system releasing drug in a controlled manner to achieve a therapeutic goal for the effective treatment of breast… read more here.
Keywords: paclitaxel loaded; treatment breast; breast cancer; effective treatment ... See more keywords
Paclitaxel-Loaded Lipid-Coated Magnetic Nanoparticles for Dual Chemo-Magnetic Hyperthermia Therapy of Melanoma
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15030818
Abstract: Melanoma is the most aggressive and metastasis-prone form of skin cancer. Conventional therapies include chemotherapeutic agents, either as small molecules or carried by FDA-approved nanostructures. However, systemic toxicity and side effects still remain as major… read more here.
Keywords: paclitaxel loaded; ptx; melanoma; loaded lipid ... See more keywords