Could the combination of Nab-paclitaxel plus gemcitabine salvage metastatic pancreatic adenocarcinoma after folfirinox failure? A single institutional retrospective analysis.
Sign Up to like & getrecommendations! Published in 2017 at "Clinics and research in hepatology and gastroenterology"
DOI: 10.1016/j.clinre.2016.11.012
Abstract: Sex Male 10 (83.3%) Female 2 (16.7%) Age (years), median (range) 61 (52—74) Comorbidities, median (range) 1.5 (1—4) Smoking 8 (66.7%) Diabetes mellitus 6 (50%) High blood pressure 5 (41.7%) Hyperlipidemia 2 (16.7%) Pancreatic tumor… read more here.
Keywords: nab paclitaxel; could combination; range; combination nab ... See more keywords
P3.01-15 Efficacy of Paclitaxel Plus TS1 Against Non-Small Cell Lung Cancer Previously Treated
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Thoracic Oncology"
DOI: 10.1016/j.jtho.2018.08.1575
Abstract: NCI-H460 cells with mutant PIK3CA and KRASgenes. Finally, the effect of radiation on EMT-associated markers was also assessed, revealing that mTORC1 inhibition couldalleviate irradiation-specific EMT changesin NCI-H661 cells. Conclusion: these data suggest that mTORC1 inhibition… read more here.
Keywords: plus ts1; small cell; ts1 non; non small ... See more keywords
Neoadjuvant chemotherapy with liposomal paclitaxel plus platinum for locally advanced esophageal squamous cell cancer: Results from a retrospective study
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DOI: 10.1111/1759-7714.14328
Abstract: This study analyzed the efficacy and safety of neoadjuvant chemotherapy with liposomal paclitaxel plus platinum in patients with locally advanced resectable esophageal squamous cell carcinoma (ESCC). read more here.
Keywords: locally advanced; plus platinum; neoadjuvant chemotherapy; paclitaxel plus ... See more keywords
Phase I, multicenter, open-label study of intravenous VCN-01 oncolytic adenovirus with or without nab-paclitaxel plus gemcitabine in patients with advanced solid tumors
Sign Up to like & getrecommendations! Published in 2022 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2021-003255
Abstract: Background VCN-01 is an oncolytic adenovirus (Ad5 based) designed to replicate in cancer cells with dysfunctional RB1 pathway, express hyaluronidase to enhance virus intratumoral spread and facilitate chemotherapy and immune cells extravasation into the tumor.… read more here.
Keywords: paclitaxel plus; plus gemcitabine; patients advanced; nab paclitaxel ... See more keywords
A phase II Study of FOLFOX versus POF (paclitaxel plus FOLFOX) versus IP PAC (intraperitoneal paclitaxel) plus FOLFOX as a first-line treatment in advanced gastric cancer (AGC): A feasibility analysis.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.4_suppl.56
Abstract: 56Background: Double regimens are commonly accepted for AGC in East Asia. However, triple regimens are recommended in west countries. POF regimen (a modified DCF reported in 2007, 2008, 2009, 2010 ASCO) appeared to be of… read more here.
Keywords: folfox versus; paclitaxel plus; plus folfox; paclitaxel ... See more keywords
Exploratory study of intraperitoneal paclitaxel plus mFOLFOX6 for gastric cancer patients with peritoneal metastasis and inadequate oral intake.
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DOI: 10.1200/jco.2017.35.4_suppl.tps222
Abstract: TPS222Background: Systemic chemotherapy with oral fluoropyrimidine and platinum is recommended for the first-line treatment for unresectable or recurrent gastric cancer in Japan. However, some pati... read more here.
Keywords: gastric cancer; intraperitoneal paclitaxel; exploratory study; cancer ... See more keywords
Paclitaxel plus nedaplatin vs. paclitaxel plus carboplatin in women with epithelial ovarian cancer: A multi-center, randomized, open-label, phase III trial.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.e17519
Abstract: e17519Background: The multi-center, randomized, open-lable, phaseⅢ trial discussed in the present study was performed to compare clinical outcomes of nedaplatin (NDP) plus paclitaxel, and carboplat... read more here.
Keywords: randomized open; multi center; center randomized; paclitaxel plus ... See more keywords
POF (paclitaxel plus FOLFOX) versus IP PAC (intraperitoneal paclitaxel plus FOLFOX) versus FOLFOX as a first-line treatment in advanced gastric cancer (AGC): Update from a multicenter, randomized phase II trial, FNF-004 trial.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.4035
Abstract: 4035 Background: The PFS with POF was statistically significantly improved and IP PAC was trending to improve compared to FOLFOX in first-line setting in AGC were reported in 2019 ASCO-GI (abstract 6). Update and subgroup… read more here.
Keywords: paclitaxel plus; folfox versus; pac; paclitaxel ... See more keywords
Comparison of efficacy and safety of second-line palliative chemotherapy with paclitaxel plus raltitrexed and paclitaxel alone in patients with metastatic gastric adenocarcinoma: A randomized phase II trial.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.4054
Abstract: 4054 Background: Paclitaxel is a microtubule stabilizing agent that has been the standard second line chemotherapy in the treatment of advanced gastric cancer. This study was designed to find out the clinical outcome of paclitaxel… read more here.
Keywords: chemotherapy; paclitaxel plus; paclitaxel; second line ... See more keywords
Clinical feasibility of curative surgery after nab-paclitaxel plus gemcitabine-cisplatin chemotherapy in patients with locally advanced cholangiocarcinoma.
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DOI: 10.1200/jco.2022.40.4_suppl.387
Abstract: BACKGROUND This study was conducted to evaluate the clinical feasibility of nab-paclitaxel plus gemcitabine-cisplatin triplet chemotherapy in patients with locally advanced cholangiocarcinoma in real-world practice. METHODS We retrospectively reviewed patients with locally advanced cholangiocarcinoma who… read more here.
Keywords: locally advanced; paclitaxel plus; advanced cholangiocarcinoma; plus gemcitabine ... See more keywords
Comparative effectiveness and safety of nab-paclitaxel plus carboplatin vs gemcitabine plus carboplatin in first-line treatment of advanced squamous cell non-small cell lung cancer in a US community oncology setting
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DOI: 10.2147/lctt.s139647
Abstract: Introduction Real-world comparative effectiveness, safety, and supportive care use of nab-paclitaxel plus carboplatin vs gemcitabine plus platinum were analyzed in patients with advanced or metastatic squamous cell non-small cell lung cancer (NSCLC). Materials and methods… read more here.
Keywords: gemcitabine plus; nab paclitaxel; paclitaxel plus; plus carboplatin ... See more keywords