Hypoxia-Activated PEGylated Paclitaxel Prodrug Nanoparticles for Potentiated Chemotherapy.
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DOI: 10.1021/acsnano.2c05341
Abstract: Developing controlled drug-release systems is imperative and valuable for increasing the therapeutic index. Herein, we synthesized hypoxia-responsive PEGylated (PEG = poly(ethylene glycol)) paclitaxel prodrugs by utilizing azobenzene (Azo) as a cleavable linker. The as-fabricated prodrugs… read more here.
Keywords: paclitaxel prodrug; activated pegylated; hypoxia; pap nps ... See more keywords