Articles with "pact" as a keyword



Deep Learning Enhances Multiparametric Dynamic Volumetric Photoacoustic Computed Tomography In Vivo (DL‐PACT)

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Published in 2022 at "Advanced Science"

DOI: 10.1002/advs.202202089

Abstract: Photoacoustic computed tomography (PACT) has become a premier preclinical and clinical imaging modality. Although PACT's image quality can be dramatically improved with a large number of ultrasound (US) transducer elements and associated multiplexed data acquisition… read more here.

Keywords: dynamic volumetric; computed tomography; multiparametric dynamic; pact ... See more keywords

Exploring the efficacy of photodynamic antimicrobial chemotherapy on diabetic foot ulcers in rats

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Published in 2024 at "Journal of Biophotonics"

DOI: 10.1002/jbio.202300568

Abstract: We investigate the efficacy of photodynamic antimicrobial chemotherapy (PACT) and its combination with an antibiotic in the treatment of diabetic foot ulcers (DFUs) in rats using a novel cationic amino acid porphyrin‐based photosensitizer. The research… read more here.

Keywords: antimicrobial chemotherapy; pact antibiotic; photodynamic antimicrobial; pact ... See more keywords

Coherent‐Excitation PACT With Frequency‐Compensated Reconstruction for High‐Contrast Deep‐Tissue Imaging

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Published in 2025 at "Journal of Biophotonics"

DOI: 10.1002/jbio.202500175

Abstract: Photoacoustic computed tomography (PACT) synergizes optical absorption contrast with ultrasonic resolution for noninvasive biomedical imaging yet faces limitations in signal‐to‐noise ratio (SNR), resolution, and contrast. This study introduces a coherent‐excitation PACT system integrating interferometric optical… read more here.

Keywords: excitation pact; frequency compensated; coherent excitation; contrast ... See more keywords

Photodynamic antimicrobial chemotherapy (PACT) using toluidine blue inhibits both growth and biofilm formation by Candida krusei

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Published in 2017 at "Lasers in Medical Science"

DOI: 10.1007/s10103-017-2428-y

Abstract: Among non-albicans Candida species, the opportunistic pathogen Candida krusei emerges because of the high mortality related to infections produced by this yeast. The Candida krusei is an opportunistic pathogen presenting an intrinsic resistance to fluconazol.… read more here.

Keywords: pact; krusei; growth biofilm; biofilm formation ... See more keywords

Impact of Evidence-Based Quality Improvement on Tailoring VA’s Patient-Centered Medical Home Model to Women Veterans’ Needs

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Published in 2024 at "Journal of General Internal Medicine"

DOI: 10.1007/s11606-024-08647-4

Abstract: Women Veterans’ numerical minority, high rates of military sexual trauma, and gender-specific healthcare needs have complicated implementation of comprehensive primary care (PC) under VA’s patient-centered medical home model, Patient Aligned Care Teams (PACT). We deployed… read more here.

Keywords: team; women veterans; readiness; care ... See more keywords

(The absence of) ‘Integration’ in the new pact on migration and asylum

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Published in 2025 at "ERA Forum"

DOI: 10.1007/s12027-025-00834-y

Abstract: ‘Integration’, despite being mentioned as one of the key features of the New Pact on Immigration and Asylum, is relatively absent in the Pact itself. This article reflects on how the New Pact will influence… read more here.

Keywords: integration; asylum; migration; absence integration ... See more keywords

Photodynamic Antimicrobial Chemotherapy (PACT), using Toluidine blue O inhibits the viability of biofilm produced by Candida albicans at different stages of development.

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Published in 2018 at "Photodiagnosis and photodynamic therapy"

DOI: 10.1016/j.pdpdt.2017.12.001

Abstract: BACKGROUND Candida albicans is an opportunistic fungus producing both superficial and systemic infections, especially in immunocompromised individuals. It has been demonstrated that C. albicans ability to form biofilms is a crucial process for colonization and… read more here.

Keywords: viability; pact; biofilm; different stages ... See more keywords

Photodynamic Antimicrobial Chemotherapy Action of Phenothiazinium Dyes in Planktonic Candida albicans is increased in Sodium Dodecyl Sulfate.

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Published in 2019 at "Photodiagnosis and photodynamic therapy"

DOI: 10.1016/j.pdpdt.2019.101612

Abstract: BACKGROUND Photodynamic antimicrobial chemotherapy (PACT) is an important therapeutic platform for antimicrobial activity, especially due to the resistant strains, however, the physical-chemical properties of the photosensitizers may affect the final outcome. Recently, this research group… read more here.

Keywords: photodynamic antimicrobial; pact action; antimicrobial chemotherapy; pact ... See more keywords

Smart hydrogel-based DVDMS/bFGF nanohybrids for antibacterial phototherapy with multiple damaging-sites and accelerated wound healing.

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Published in 2020 at "ACS applied materials & interfaces"

DOI: 10.1021/acsami.0c00298

Abstract: Burn infection is one of the commonest causes of death in severely burned patients. Developing multifunctional biological nanomaterials have a great significance for the comprehensive treatment of burn infection. In this paper, we developed a… read more here.

Keywords: wound healing; burn infection; hydrogel based; treatment ... See more keywords

PACT prevents aberrant activation of PKR by endogenous dsRNA without sequestration

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Published in 2025 at "Nature Communications"

DOI: 10.1038/s41467-025-58433-x

Abstract: The innate immune sensor PKR for double-stranded RNA (dsRNA) is critical for antiviral defense, but its aberrant activation by cellular dsRNA is linked to various diseases. The dsRNA-binding protein PACT plays a critical yet controversial… read more here.

Keywords: pact prevents; pkr; aberrant activation; pact ... See more keywords

Why develop photoactivated chemotherapy?

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Published in 2018 at "Dalton transactions"

DOI: 10.1039/c8dt01585f

Abstract: Photoactivated chemotherapy is an approach where a biologically active compound is protected against interaction with the cell environment by a light-cleavable protecting group, and unprotected by light irradiation. As such, PACT represents a major scientific… read more here.

Keywords: photoactivated chemotherapy; pact; develop photoactivated; compound ... See more keywords