Pegaspargase: A Review in Acute Lymphoblastic Leukaemia
Sign Up to like & getrecommendations! Published in 2019 at "Drugs"
DOI: 10.1007/s40265-019-01120-1
Abstract: Pegaspargase (Oncaspar®), a pegylated form of native Escherichia coli-derived l-asparaginase (hereafter referred as E. colil-asparaginase), is indicated in the USA and EU for the treatment of acute lymphoblastic leukaemia (ALL) as a component of multi-agent… read more here.
Keywords: colil asparaginase; treatment; pegaspargase; paediatric adult ... See more keywords
Whole-body magnetic resonance imaging: Incidental findings in paediatric and adult populations.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of radiology"
DOI: 10.1016/j.ejrad.2020.109156
Abstract: PURPOSE To determine the prevalence and characterise the significance of incidental findings on whole-body MRI in paediatric and adult populations. METHODS A retrospective, single-institution study over a period of 8 years. The study population comprised… read more here.
Keywords: incidental findings; paediatric adult; whole body; body mri ... See more keywords
Transition from paediatric to adult care in patients with mucopolysaccharidosis (MPS)
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Genetics and Metabolism"
DOI: 10.1016/j.ymgme.2018.12.223
Abstract: Mucopolysaccharidoses (MPS) are rare disorders associated with enzyme deficiencies, resulting in glycosaminoglycan (GAG) accumulation in multiple organ systems. Because of improvements to the diagnosis and treatment of MPS, patients are increasingly surviving to adulthood, and… read more here.
Keywords: care; adult care; transfer; paediatric adult ... See more keywords
Paediatric and adult congenital cardiology education and training in Europe.
Sign Up to like & getrecommendations! Published in 2022 at "Cardiology in the young"
DOI: 10.1017/s104795112100528x
Abstract: BACKGROUND Limited data exist on training of European paediatric and adult congenital cardiologists. METHODS A structured and approved questionnaire was circulated to national delegates of Association for European Paediatric and Congenital Cardiology in 33 European… read more here.
Keywords: paediatric cardiology; congenital cardiology; training; cardiology ... See more keywords
CDK4/6 inhibition presents as a therapeutic option for paediatric and adult germ cell tumours and induces cell cycle arrest and apoptosis via canonical and non-canonical mechanisms
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DOI: 10.1038/s41416-020-0891-x
Abstract: Background Germ cell tumours (GCTs) are the most common solid malignancies in young men. Although high cure rates can be achieved, metastases, resistance to cisplatin-based therapy and late toxicities still represent a lethal threat, arguing… read more here.
Keywords: cell; paediatric adult; cell cycle; apoptosis ... See more keywords
Transition of care from paediatric to adult age for rare chronic disorders: an Italian experience
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Public Health"
DOI: 10.1093/eurpub/ckaa166.919
Abstract: Transition of care represents the transfer from child to adult care. An effective transition maintains continuity of care and presents better clinical outcomes. Thanks to improved survivorship of chronic paediatric patients to adulthood, this process… read more here.
Keywords: transition; transition care; model; care ... See more keywords
Transitioning from paediatric to adult rheumatological healthcare: English summary of the Japanese Transition Support Guide.
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DOI: 10.1093/mr/roab071
Abstract: Issues related to transitioning from paediatric to adult healthcare are currently receiving international attention. In Japan, 1000 patients with childhood-onset chronic rheumatological diseases reach adulthood every year and require transition from care by paediatric to… read more here.
Keywords: support; adult; care; paediatric adult ... See more keywords
Mucosal antibody response to SARS-CoV-2 in paediatric and adult patients: a longitudinal study
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DOI: 10.1101/2021.09.27.21264219
Abstract: Conjunctival and nasal mucosal antibody responses in thirty-four paediatric and forty-seven adult COVID-19 patients were measured. The mucosal antibody was IgA dominant. In the nasal epithelial lining fluid (NELF) of asymptomatic paediatric patients, SARS-CoV-2 spike… read more here.
Keywords: sars cov; mucosal antibody; iga; adult patients ... See more keywords
Transfer from paediatric to adult care for young adults with Type 2 diabetes: the SEARCH for Diabetes in Youth Study
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DOI: 10.1111/dme.13589
Abstract: To describe factors associated with transfer from paediatric to adult care and poor glycaemic control among young adults with Type 2 diabetes, using the SEARCH for Diabetes in Youth study. read more here.
Keywords: transfer paediatric; adult care; type diabetes; adults type ... See more keywords
Impact of first COVID‐19 lockdown on paediatric and adult haemophilia patients treated in a French Haemophilia Comprehensive Care Centre
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DOI: 10.1111/hae.14526
Abstract: The coronavirus disease 2019 (COVID‐19) pandemic has created an unprecedented global health crisis. read more here.
Keywords: impact first; covid lockdown; lockdown paediatric; paediatric adult ... See more keywords
Pathophysiology, causes and genetics of paediatric and adult bronchiectasis
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DOI: 10.1111/resp.13509
Abstract: Bronchiectasis has historically been considered to be irreversible dilatation of the airways, but with modern imaging techniques it has been proposed that ‘irreversible’ be dropped from the definition. The upper limit of normal for the… read more here.
Keywords: bronchiectasis; causes genetics; pathophysiology causes; genetics ... See more keywords