Clinical outcomes of second relapsed and refractory first relapsed paediatric AML: A retrospective study within the NOPHO-DB SHIP consortium.
Sign Up to like & getrecommendations! Published in 2022 at "British journal of haematology"
DOI: 10.1111/bjh.18039
Abstract: As treatments for second relapsed and refractory first relapsed paediatric AML transition from purely palliative to more commonly curative in nature, comparative data is necessary for evaluating the effectiveness of emerging treatment options. Furthermore, little… read more here.
Keywords: refractory first; second relapsed; paediatric aml; relapsed paediatric ... See more keywords
Immunophenotypically defined stem cell subsets in paediatric AML are highly heterogeneous and demonstrate differences in BCL‐2 expression by cytogenetic subgroups
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Haematology"
DOI: 10.1111/bjh.18094
Abstract: In adult acute myeloid leukaemia (AML), immunophenotypic differences enable discrimination of leukaemic stem cells (LSCs) from healthy haematopoietic stem cells (HSCs). However, immunophenotypic stem cell characteristics are less explored in paediatric AML. Employing a 15‐colour… read more here.
Keywords: stem cell; expression; stem; paediatric aml ... See more keywords