Articles with "paediatric cancers" as a keyword



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Pan-cancer genome and transcriptome analyses of 1,699 pediatric leukemias and solid tumors

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Published in 2018 at "Nature"

DOI: 10.1038/nature25795

Abstract: Analysis of molecular aberrations across multiple cancer types, known as pan-cancer analysis, identifies commonalities and differences in key biological processes that are dysregulated in cancer cells from diverse lineages. Pan-cancer analyses have been performed for… read more here.

Keywords: pan cancer; cancer genome; transcriptome analyses; genome transcriptome ... See more keywords
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Hypoxia and its therapeutic possibilities in paediatric cancers

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Published in 2020 at "British Journal of Cancer"

DOI: 10.1038/s41416-020-01107-w

Abstract: In tumours, hypoxia—a condition in which the demand for oxygen is higher than its availability—is well known to be associated with reduced sensitivity to radiotherapy and chemotherapy, and with immunosuppression. The consequences of hypoxia on… read more here.

Keywords: therapeutic possibilities; hypoxia therapeutic; paediatric cancers; biology ... See more keywords