Shortening the decade‐long gap between adult and paediatric drug formulations: a new framework based on the HIV experience in low‐ and middle‐income countries
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the International AIDS Society"
DOI: 10.1002/jia2.25049
Abstract: Despite the coordinated efforts by several stakeholders to speed up access to HIV treatment for children, development of optimal paediatric formulations still lags 8 to 10 years behind that of adults, due mainly to lack… read more here.
Keywords: paediatric drug; shortening decade; drug formulations; decade long ... See more keywords
How paediatric drug development and use could benefit from OMICs: A c4c expert group white paper
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.15216
Abstract: The safety and efficacy of pharmacotherapy in children, particularly preterms, neonates and infants, is limited by a paucity of good‐quality data from prospective clinical drug trials. A specific challenge is the establishment of valid biomarkers.… read more here.
Keywords: paediatric drug; omics technologies; drug development; drug ... See more keywords
11 Clinical, methodological and patient/parent expert advice in paediatric drug development via conect4children
Sign Up to like & getrecommendations! Published in 2023 at "Archives of Disease in Childhood"
DOI: 10.1136/archdischild-2023-esdppp.11
Abstract: Introduction Children have the right to new and improved medicines.conect4children (c4c) aims to promote innovative trial design to optimise paediatric development plans while ensuring the voice of young patients and their families is heard. To… read more here.
Keywords: paediatric drug; advice; methodology; development ... See more keywords